Tag Archives: Acute Diseases

Post #48 – Is cancer preventable through optimal healthy living?

10 Sunday Jan 2016

Posted by in Causes of Death, Ideal Body Weight, Living to 120, Nutrition, Optimal Exercise, Optimal Health, Optimal Nutrition, Supplements, Uncategorized, Vitality, wellness

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My wife Kimberly was telling me the other day that 2015 has been quite a remarkable year in that we had several cancer episodes among our friends and families.  Even a couple of them died.

So, that got me thinking… is cancer preventable through optimal healthy living?

What is cancer anyways?

According National Institute of Health (NIH), National Cancer Institute (NCI) website www.cancer.gov, cancer is the name given to a collection of related diseases. In all types of cancer, some of the body’s cells begin to divide without stopping and spread into surrounding tissues.

Cancer can start almost anywhere in the human body, which is made up of trillions of cells. Normally, human cells grow and divide to form new cells as the body needs them. When cells grow old or become damaged, they die, and new cells take their place.

When cancer develops, however, this orderly process breaks down. As cells become more and more abnormal, old or damaged cells survive when they should die, and new cells form when they are not needed. These extra cells can divide without stopping and may form growths called tumors.

Many cancers form solid tumors, which are masses of tissue. Cancers of the blood, such as leukemias, generally do not form solid tumors.

Cancerous tumors are malignant, which means they can spread into, or invade, nearby tissues. In addition, as these tumors grow, some cancer cells can break off and travel to distant places in the body through the blood or the lymph system and form new tumors far from the original tumor.

A cancer that has spread from the place where it first started to another place in the body is called metastatic cancer. Under a microscope, metastatic cancer cells generally look the same as cells of the original cancer.

How does cancer arise?

Cancer is a genetic disease—that is, it is caused by changes to genes that control the way our cells function, especially how they grow and divide. Three main types of genes may be involved—proto-oncogenes or genes involved in normal cell growth, tumor suppressor genes, and DNA repair genes. These changes are sometimes called “drivers” of cancer.

Genetic changes that cause cancer can be inherited from our parents. They can also arise during a person’s lifetime as a result of errors that occur as cells divide or because of damage to DNA caused by certain environmental exposures. Cancer-causing environmental exposures include substances, such as the chemicals in tobacco smoke, and radiation, such as ultraviolet rays from the sun. (Our Cancer Causes and Risk Factors page has more information.)

Inherited genetic mutations play a major role in about 5 to 10 percent of all cancers. Researchers have associated mutations in specific genes with more than 50 hereditary cancer syndromes, which are disorders that may predispose individuals to developing certain cancers.

How to prevent cancer?

So, now finally getting to the topic we started with – how to prevent cancer. Here are the four major ways to help prevent cancer:

  1. Avoid or control things known to cause cancer.
  2. Changes in diet and lifestyle.
  3. Finding precancerous conditions early. Precancerous conditions are conditions that may become cancer.
  4. Chemoprevention (medicines to treat a precancerous condition or to keep cancer from starting).

Let us take these items one at a time.

  1. Avoid or control things known to cause cancer.

Factors that are known to increase the risk of cancer:

  • Cigarette Smoking and Tobacco Use
  • Infections: HPV, Hepatitis B and C, Espstein-Barr virus, Helcobater pylori
  • Radiation: Ultraviolet sunlight, medical radiation, radon gas in homes
  • Immunosuppressive Medicines
  1. Changes in diet and lifestyle

Factors that may affect the risk of cancer:

  • Diet
  • Alcohol
  • Physical Activity
  • Obesity
  • Environmental Risk Factors: second hand smoke, asbestos, air pollution, pesticides, arsenic in drinking ware

Diet is anything we put in our mouths on a regular basis.

Diet is always a controversial subject. Media loves to talk about any new tidbit that comes out through research regarding diet.

Some studies show that fruits and non-starchy vegetables may protect against cancers of the mouth, esophagus, and stomach. Fruits may also protect against lung cancer.

Some studies have shown that a diet high in fat, proteins, calories, and red meat increases the risk of colorectal cancer, but other studies have not shown this.

It is not known if a diet low in fat and high in fiber, fruits, and vegetables lowers the risk of colorectal cancer.

According to American Cancer Society website www.cancer.org, here are the dietary guidelines to prevent cancer:

  • Be as lean as possible throughout life without being underweight.
  • Avoid excess weight gain at all ages. For those who are overweight or obese, losing even a small amount of weight has health benefits and is a good place to start.
  • Choose foods and drinks in amounts that help you get to and maintain a healthy weight.
  • Limit how much processed meat and red meat you eat.
  • Eat at least 2½ cups of vegetables and fruits each day.
  • Choose whole grains instead of refined grain products.
  • Avoid alcohol or drink no more than 1 drink per day for women or 2 per day for men.

T. Colin Campbell, PhD distills his 30 years of research on cancer and diet in “The China Study”. He concludes that a vegan diet minimizes the risk of all types of cancers as well as many other types of health risks.

For Physical Activity, American Cancer Society recommendation is for cancer prevention:

  • Exercise:
    • Adults: Get at least 150 minutes of moderate intensity or 75 minutes of vigorous intensity activity each week (or a combination of these), preferably spread throughout the week.
    • Children and teens: Get at least 1 hour of moderate or vigorous intensity activity each day, with vigorous activity on at least 3 days each week.
  • Limit sedentary behavior such as sitting, lying down, watching TV, and other forms of screen-based entertainment.

Doing some physical activity above usual activities, no matter what one’s level of activity, can have many health benefits.

  1. Finding cancer or precancerous conditions early. Precancerous conditions are conditions that may become cancer.

Then there is the matter of “early detection and early cure.”

Cancer is a group of diseases that can cause almost any sign or symptom. The signs and symptoms will depend on where the cancer is, how big it is, and how much it affects the organs or tissues. If a cancer has spread (metastasized), signs or symptoms may appear in different parts of the body.

 Treatments work best when cancer is found early – while it’s still small and is less likely to have spread to other parts of the body. This often means a better chance for a cure, especially if the cancer can be removed with surgery.

A good example of the importance of finding cancer early is melanoma skin cancer. It can be easy to remove if it has not grown deep into the skin. The 5-year survival rate (percentage of people who live at least 5 years after diagnosis) at this early stage is around 98%. Once melanoma has spread to other parts of the body, the 5-year survival rate drops to about 16%.

Some symptoms, such as tiredness or coughing, are more likely caused by something other than cancer. Symptoms can seem unimportant, especially if there’s a clear cause or the problem only lasts a short time. In the same way, a person may reason that a symptom like a breast lump is probably a cyst that will go away by itself. But no symptom should be ignored or overlooked, especially if it has lasted a long time or is getting worse.

Most likely, symptoms are not caused by cancer, but it’s important to have them checked out, just in case. If cancer is not the cause, a doctor can help figure out what the cause is and treat it, if needed.

These days it is not that difficult to get one’s genome mapped and find out any cancer syndromes that might be present and actively take the necessary preventative actions.

The American Cancer Society recommends these cancer screening guidelines for early detection of cancer  for most adults. Screening tests are used to find cancer before a person has any symptoms.

  1. Chemoprevention (medicines to treat a precancerous condition or to keep cancer from starting).

Chemoprevention is the use of substances to lower the risk of cancer, or keep it from recurring. The substances may be natural or made in the laboratory. Some chemopreventive agents are tested in people who are at high risk for a certain type of cancer. The risk may be because of a precancerous condition, family history, or lifestyle factors.

Some chemoprevention studies have shown good results. For example, selective estrogen receptor modulators (SERMS) such as tamoxifen or raloxifene have been shown to reduce the risk of breast cancer in women at high risk. Finasteride and dutasteride have been shown to reduce the risk of prostate cancer.

Bottomline

Cancer is a genetic disease that may be the result of either mutated inherited genes or the ones occur later due to health, lifestyle and environment issues.  Only about 5 to 10% of the risk of cancer is due to mutated inherited genes.

Yes, healthy lifestyle choices we have been discussing in other blog posts do lead to decreasing the chances of cancer.  To minimize the risk of cancer:

  1. Be of Lean weight
  2. Eat clean with lots of fruits and vegetables and only sparing amount of white meats
  3. Avoid the use of alcohol or tobacco
  4. Avoid second-hand smoke, pesticides and other environmental carcinogens
  5. Stay active and exercise
  6. Get regular checkups and screening tests
  7. In case of any signs or symptoms, get a quick check up to rule out any cancerous or precancerous condition.

 

Your thoughts on this subject?

Would love to hear, learn and share information.

If possible, please do leave comment in the blog itself, so others can share and learn.

Post #40 – How much Sun exposure should you have for Optimal Health?

08 Monday Jun 2015

Posted by in Aging, Optimal Health, Supplements

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A couple of weeks ago my wife and I took a vacation in the Exuma Islands in the Bahamas to celebrate our 30th wedding anniversary. Now everyone knows what Bahamas Islands have plenty of: Water and the Sun. Lounging on the beach and swimming in the ocean with all shades of turquoise, we definitely got plenty of both water and the Sun. Case in point, this picture of me!

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And, that got me thinking: So, how much Sun exposure one should have for optimal health?

On the positive side, we know that being in the Sun is very therapeutic. It cheers us up. Both because it is good for our disposition and it is a major source of Vitamin D.

On the other hand, we have all heard of skin cancer, eye damage and hypersensitivity that excessive exposure to sun can cause.

So, how do we balance the two for Optimal Health?

First, how much Sun do we need for daily dose of Vitamin D?

Most of the “experts” sort of punt this question saying that there isn’t one recommendation for everyone. This is because the amount of time you need to spend in the sun for your skin to make enough vitamin D depends on a number of factors. These include your skin type (how dark your skin is or how easily you get sunburnt), the time of year and what time of day it is.

In the Northern Hemisphere, (e.g., US, Canada) short daily periods of sun exposure without sunscreen during the summer months (April to October) are enough for most people to make enough vitamin D. Evidence suggests that the most effective time of day for vitamin D production is between 11am and 3pm.

A short period of time in the sun means just a few minutes – evidence suggests that about 10 to 15 minutes is enough for most lighter-skinned people – and is less than the time it takes you to start going red or burn.

The larger the area of skin that is exposed to sunlight, the more chance there is of making enough vitamin D before you start to burn. People with darker skin will need to spend longer in the sun to produce the same amount of vitamin D.

In the Northern Hemisphere, our skin isn’t able to make vitamin D from winter sunlight (November to March) as the sunlight hasn’t got enough UVB (ultraviolet B) radiation. During the winter, we get vitamin D from our body’s stores and from food sources. Hence great emphasis on Vitamin D supplements in the US and other countries in the Northern Hemisphere located at higher latitudes.

How much sun before you do damage to the Skin?

Now on to how much sun is needed to produce sun damage to the skin. Here also the clear answer is: It depends.

In research, often the measurement of damage used is the amount of UV radiation needed to cause erythema – the red flushing of the skin caused by exposure to sunlight. The theory is that more the erythema, the greater is the likelihood of damage and cancer.

Because of the variables of geography and seasons, and variations in how an individual reacts to sunlight, it isn’t possible to come up with hard and fast rules – but here are some useful guidelines.

Avoid the midday sun

The time when the skin makes most Vitamin D is when it’s exposed to the midday summer sun – but that’s the time the skin is most easily damaged.

However, redness can occur in only eight minutes in a mid-day sun.

So in peak summer times from 10 am to 3pm, you should use protection against the sun; shade, hats, clothing, sunglasses and sunscreen.

But earlier in the day and later in the afternoon, for a similar period of sun exposure and vitamin D manufacture, you get much less skin damage.

During the summer months in the Southern states in the US, for example, 10 to 15 minutes of unprotected sun exposure of the face, arms and hands before 10am or after 3pm, three to four times a week, will give you enough Vitamin D without skin damage.

But this may not be enough in Northern part of the US or Canada, especially in winter. You’ll need longer periods of exposure or more flesh exposed to the sun.

Longer for dark skins

Note that the figures only apply to fair skinned people. People with very dark skin need around six times more exposure to UV radiation to produce as much vitamin D as someone with fair skin. These people may need sunlight exposure during peak times – i.e. the middle of the day – especially in the Northern states in the winter months.

On the other hand people with darker skins are less likely to get skin damage because of greater amounts of pigment in their skin. Even though they are still susceptible to getting skin cancer.

Bottom Line

Based on what I just learned, for Optimal Health, I am going to stick to my Vitamin D supplements to get sufficient Vitamin D, year-round and heed to the following recommendation I found on the Skin Cancer Foundation website:

Q: I’m going to the Caribbean this winter. Are there any special precautions I need to take to protect myself from the sun?

A: (By Neil Sadick, MD, FAAD, FAACS, FACP, FACPh) When the days get colder and the nights get longer many people enjoy a vacation to a warm place like the Caribbean, to catch some sun and “recharge their batteries.” Typical winter vacation regions are located close to the equator, with little distinction between the seasons and high temperatures year-round. The sunny weather in these regions is accompanied by strong ultraviolet (UV) radiation, as the sun’s rays hit the earth at a more direct angle and aren’t as well-absorbed by the atmosphere.

Furthermore, these sunny days tend to be long, sometimes with substantial amounts of UV until early evening. The ability to travel from a winter season to a sunny vacation spot in just a few hours is a great comfort in modern times, but also a heavy burden for the skin. Current studies now show that sun-filled vacations and sunburns play a key role in the development of melanoma, the most dangerous form of skin cancer.

Intermittent, intense sun exposure, the kind you are likely to receive on a sun-drenched winter vacation (the sort that often leads to sunburn), is associated with a much higher melanoma risk than regular, everyday sun exposure. Suffering one or more blistering sunburns in childhood or adolescence, or five or more by any age, more than doubles a person’s lifetime chances of developing melanoma. Important precautions that protect you from the sun on your vacation include shade, sun-protective clothing, and sunscreen, as well as sensibly limiting your sun exposure in general.

The sunscreen you use should have a sun protection factor of at least 30 and sufficiently block UVA as well as UVB rays. (Look for “broad spectrum” or “multi-spectrum” protection.) If you’ll be vacationing near the water, a water-resistant or very water-resistant sunscreen formula is recommended. Apply approximately one ounce of sunscreen (two tablespoons) to the whole body, and reapply every two hours or immediately after activities such as swimming, sweating, or rubbing/wiping.

Loose-fitting, long-sleeved shirts and long pants made from tightly woven fabrics offer the best protection from the sun’s UV rays. You may want to look for clothes that have a UPF (ultraviolet protection factor) label of 30+; a shirt with a UPF of 30, for example, will let just 1/30th of the sun’s UV radiation reach your skin. High-UPF athletic gear may be particularly helpful, since such clothes are meant to keep you cool and comfortable, no matter how hot the weather gets.

Finally, a hat with a brim at least 3” all the way around and UV-blocking sunglasses will also help protect the vulnerable skin on your head, face, neck, and tops of the shoulders. Sensible sun behavior means avoiding tanning and burning as well as seeking the shade between 10 AM and 4 PM (and especially between noon and 2 PM, when the sun’s rays are strongest).

What are your thoughts on this topic?

I would love to learn from you and share that knowledge with others.

Post #13 – Ever heard of Functional Medicine?

27 Tuesday May 2014

Posted by in Aging, Functional Medicine, Living to 120, Reversing Chronic Diseases, Vigor, Vitality

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In my previous blog posts, I have talked about curing my allergies, fixing migraines, and curing a whole host of other issues without pharmacological medicines. Yes, actually curing these issues and not just managing or controlling the symptoms.

For the longest amount of time, I found it difficult to talk about to these things with my physicians or even lay people. I must admit it all sounded so much like woo doo even to me as I would talk about it. A common refrain from doctors was, “We only practice evidence based medicine.” I did not know what to believe or not believe, except that from my personal experience (evidence of n=1), I could prove that these things work.

All that changed, when last year Kimberly and I attended the Health and Wellness Conference 2013 at the University of Maryland, School of Medicine at the Center of Integrative Medicine in Baltimore, Maryland. There we heard talks about yoga, Qi Gong, nutrition, meditation, detoxing, and many other so called “alternative” therapies in the setting of Evidence Based Medicine.

Key note speaker was Mark Hyman, MD. He has a private practice Ultra Wellness Center in Massachusetts. He wrote a book, The Blood Sugar Solution, which received endorsement from President Bill Clinton. He talked about the diagnosis and cure of Diabesity, a term he has coined as combination of diabetes and obesity. And, he talked about diabesity in the context of what he called Functional Medicine.

Since then I have studied up quite a bit on Functional Medicine and I do believe that many of my conversations in my blog posts fit in that framework. More I dig into this topic the more entranced I am getting with this topic. I feel that functional medicine is the key to the kingdom, when it comes to wellness, vitality and living the optimal health span and life span.

Jeffrey Bland, Ph.D. is considered “father” of this field. Mark Hyman calls him his mentor. Among Bland’s other accomplishments, he has founded Personalized Lifestyle Medicine Institute and The Institute for Functional Medicine. Recently, he has written a book, “The Disease Delusion, Conquering the Causes of Chronic Illness for a Healthier, Longer, and Happier Life.”

Institute for functional medicine describes functional medicine as follows:

“Functional medicine addresses the underlying causes of disease, using a systems-oriented approach and engaging both patient and practitioner in a therapeutic partnership. It is an evolution in the practice of medicine that better addresses the healthcare needs of the 21st century. By shifting the traditional disease-centered focus of medical practice to a more patient-centered approach, functional medicine addresses the whole person, not just an isolated set of symptoms. Functional medicine practitioners spend time with their patients, listening to their histories and looking at the interactions among genetic, environmental, and lifestyle factors that can influence long-term health and complex, chronic disease. In this way, functional medicine supports the unique expression of health and vitality for each individual.”

So, the basic idea of functional medicine is to take a systems approach to disease and wellness rather than either chasing symptoms or taking germ theory approach that generally focuses on single point of correction. In his book, Jeffrey Bland talks of seven different systems for our bodies:

  1. Assimilation and Elimination
  2. Detoxification
  3. Defense
  4. Cellular Communication
  5. Cellular Transport
  6. Energy
  7. Structure

So the objective in functional medicine is to investigate symptoms to pinpoint one or more of these seven systems that are not working properly and then to change diet, exercise and lifestyle to fix the system imbalance and thereby the diseases and the symptoms.

The end result is often pretty low tech, and may seem underwhelming. That is, implement changes in diet, exercise and lifestyle to redirect expression of certain genes to cure a disease.

However, approach to getting there can be fairly high-tech in identifying the true root cause, identifying the systems that are out of balance and gene expressions that may be responsible for the underlying imbalance. And, as you see from the stories, results can be very profound and almost magical.

If you know someone, who is being treated for certain symptoms of chronic diseases by meds. e.g., high blood pressure, obesity, brain fog, constant fatigue, high cholesterol, inflammation, muscle aches, etc..  The meds being used often lead to side effects that need to be treated by other meds, which in turn are causing other side effects etc.. Such a person is the perfect candidates for functional medicine.

Have you heard of functional medicine?

Do you have any experience with functional medicine?

I have been looking for good certified functional medicine practitioners in our area that we could consult and also recommend to our friends and family. We have access to some lists, but no personal experience yet. Do you know of such a practitioner?

I would love to learn if you know someone.

Post #6 – How do we lose vitality?

06 Sunday Apr 2014

Posted by in Aging, Uncategorized, Vigor, Vitality

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So, just to be sure, my goal (and hopefully your goal) is to purposely live to 120 (or the maximum possible lifespan) with the highest attainable vitality. To achieve that, I feel, I must understand about anything that might get in the way.

In the posts so far, I have been talking about achieving the lifespan of 120 and thereby about a subject that might have sounded morbid to some of you. That is about death and dying.

Let us change our focus to the second part of the goal: Maintaining Vitality. More specifically understanding the potential hurdles to  maintaining vitality, i.e., answering the question: how do we lose vitality?

A good definition of vitality I have seen is in the Free Dictionary, as “the capacity to live, grow or develop.” A good synonym of vitality for our purpose here is vigor, including physical, mental, intellectual vigor.

You have seen it. A fried or a family member is full of vitality and then you notice that he/she starts “going downhill”. The person used to be out and about all the time, went running, then started merely walking, then walking but not as often, and then stared to just hang around the house, then on the couch more and more and then … – you get the idea. Decline happens, at times very slowly, and other times rather rapidly.

Another scenario could be that someone you know experiences a physical, mental or emotional traumatic experience and then never really recovers from it, with increasing physical pain or mental/emotional aguish rapidly goes downhill.

So, what can cause such a decline?

Well, as I started to compile a list of causes for losing vitality, I noticed that there are three broad categories: 1) acute illness, 2) chronic diseases, and 3) senescence or aging related causes. As you would suspect, there is much overlap between these categories, especially among lists for 2 and 3.

So, a list of acute illnesses may include:

  1. Tuberculosis
  2. Syphilis
  3. Typhoid
  4. Streptococcal
  5. Diphtheria
  6. Whooping Cough
  7. Smallpox
  8. Pneumonia/flu
  9. Depression
  10. Accident or Injury
  11. Heart attack
  12. Stroke
  13. Blood Clot/Thrombosis/Pulmonary Embolism
  14. Rheumatoid Arthritis
  15. Cirrhosis
  16. Kidney failure
  17. Other infectious diseases

A list of chronic diseases may include:

  1. Diabetes
  2. Coronary diseases
  3. Obesity
  4. Cancer
  5. Osteoarthritis
  6. Alzheimer’s diseases
  7. Depression
  8. Kidney diseases
  9. Liver disease
  10. High Blood Pressure

And, finally, the list of aging/senescence causes might include:

  1. Insulin resistance
  2. Hardening of the arteries
  3. Loss of muscle mass
  4. Osteoporosis or Loss of bone mass
  5. Gaining excess fat
  6. Inflammation
  7. Arthritis
  8. Stress
  9. Buildup of toxicity
  10. Loss of flexibility
  11. Loss of balance
  12. Slowing reaction times
  13. Slowing basal metabolic rate (BMR)
  14. Loss of appetite

It is interesting to ponder the implication of the overlaps between the lists.

For example, if you have known someone to have had a heart attack, it was definitely an acute illness event that probably changed their vitality curve and sent that person downhill.

Then again, may be that person was already going downhill since he/she had been losing cardio capacity due to chronic coronary disease.

And, may be the heart attack was in-part the result of hardening of the arteries due to old age.

To achieve longevity and vitality, we must overcome acute illnesses, chronic diseases and also slow the aging /senescence process.

What I am really excited about is first and foremost looking for those lifestyle activities that positively impact items on all three lists at the same time.

And, my search so far, indicates that there are such activities. The most challenging part seems to be picking through the controversies to find the optimal activities.

In any case, I think it will be an exciting journey. I look forward to sharing results of my search in the future posts.

What do you think?

Do you feel there are other hurdles that one must overcome to maintaining optimum vitality?